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Swedish experience-based value sets for EQ-5D health states

机译:基于经验的EQ-5D健康状况的价值集

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PurposeTo estimate Swedish experience-based value sets for EQ-5D health states using general population health survey data.MethodsApproximately 45,000 individuals valued their current health status by means of time trade off (TTO) and visual analogue scale (VAS) methods and answered the EQ-5D questionnaire, making it possible to model the association between the experience-based TTO and VAS values and the EQ-5D dimensions and severity levels. The association between TTO and VAS values and the different severity levels of respondents’ answers on a self-rated health (SRH) question was assessed.ResultsAlmost all dimensions (except usual activity) and severity levels had less impact on TTO valuations compared with the UK study based on hypothetical values. Anxiety/depression had the greatest impact on both TTO and VAS values. TTO and VAS values were consistently related to SRH. The inclusion of age, sex, education and socioeconomic group affected the main effect coefficients and the explanatory power modestly.ConclusionsA value set for EQ-5D health states based on Swedish valuations has been lacking. Several authors have recently advocated the normative standpoint of using experience-based values. Guidelines of economic evaluation for reimbursement decisions in Sweden recommend the use of experience-based values for QALY calculations. Our results that anxiety/depression had the greatest impact on both TTO and VAS values underline the importance of mental health for individuals’ overall HRQoL. Using population surveys is in line with recent thinking on valuing health states and could reduce some of the focusing effects potentially appearing in hypothetical valuation studies.
机译:目的使用一般人群健康调查数据估算瑞典基于EQ-5D健康状态的经验值方法。大约45,000个人通过时间权衡(TTO)和视觉模拟量表(VAS)方法评估了其当前的健康状况并回答了EQ -5D问卷,可以对基于经验的TTO和VAS值与EQ-5D维度和严重性级别之间的关联进行建模。与英国相比,评估了TTO和VAS值与受访者对自评健康(SRH)问题的回答的不同严重程度之间的关联。结果与英国相比,几乎所有维度(日常活动除外)和严重程度对TTO估值的影响都较小根据假设值进行研究。焦虑/抑郁对TTO和VAS值的影响最大。 TTO和VAS值始终与SRH相关。年龄,性别,教育程度和社会经济群体的纳入影响了主要影响系数和解释力。结论缺乏基于瑞典评估为EQ-5D健康状态设定的值。几位作者最近提倡使用基于经验的价值观的规范立场。瑞典关于报销决策的经济评估指南建议将基于经验的值用于QALY计算。我们的研究结果表明,焦虑/抑郁对TTO和VAS值的影响最大,突出了心理健康对个人总体HRQoL的重要性。使用人口调查与评估健康状况的最新想法是一致的,并且可以减少假设性评估研究中潜在出现的一些集中效应。

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